Researchers developed two computational tools to decode how cells communicate in tissues. sCCIgen creates realistic virtual ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

The interaction between cancer cells and the immune microenvironment leads to immune reprogramming and metastasis. Cancer immunoediting facilitates tumor escape from immune destruction, consequently ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

Illustration of a spatial imprint of captured transcripts by Nova-ST, along with the localization of binned clustering, for a coronal section of the mouse brain. The illustration below the brain ...

Correlation of enriched specific subset of immune cells nearby tumor associated macrophage (TAM) with pathologic complete response (pCR) of concurrent chemoradiotherapy followed by nivolumab in ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...