Building on the concept that blocking differentiation into specialized cell types maintains stem cells, USC and NIH scientists identify GSK3α as a checkpoint across diverse stem cell types. A study ...

Bacterial cell division is a fundamental biological process that ensures the propagation of life through a precisely orchestrated set of events. Central to this process is the formation of the Z ring, ...

Researchers use a light-activated protein to illuminate when embryos can cope with disruptions to cell division.Cell division ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

Checkpoint inhibitors are antibody-based cancer therapies that unlock the immune system’s natural ability to fight cancer. These treatments work by blocking special proteins called immune checkpoints, ...

Researchers have identified a shared protein checkpoint, GSK3α, that maintains stem cell identity across multiple types, potentially streamlining lab cultivation for therapies. In a separate advance, ...

In a new paper published in Cancer Research, researchers at MUSC Hollings Cancer Center have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...